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What is Ketotifen?
Ketotifen is a substance which is offered for sale under several brand names and one of them is Zaditor. That is a mast cell stabilizer and a first generation noncompetitive H1 antihistamine. In most of the cases it is sold as a salt with some fumaric acid and it comes available in two forms – ophthalmic and oral. When used in the oral form, Ketotifen is taken to prevent asthma attacks or anaphylaxis. When being used for asthma cases, the drug is not that effective for treating an immediate attack but over the time its use will reduce the duration and frequency of the attacks. It is also applied in case of different mast cell and allergic-type disorders. When taken in the ophthalmic form, Ketotifen is used in order to treat allergic conjunctivitis. That is so, as Ketotifen can relieve and can prevent eye itchiness as well as irritation, which is associated with the popular seasonal allergies. Ketotifen starts working just minutes after the drops have been administered. Users should be aware of the fact that the Ketotifen drug has not been studied among children under the age of three. They should also know that the mean elimination half-life of the drug is 12 hours. The drug has anti-histaminic activity, but is also a functional leukotriene antagonist and also a phosphodiesterase inhibitor. The oral ketotifen has been used by people who suffer from asthma and allergic rhinitis, allergic conjunctivitis and atopic dermatitis, cold-induced urticaria and chronic urticaria, exercise-induced urticaria and cholinergic urticaria, as well as in cases of systemic mast cell disease including mastocytosis, MCAS, allergic and nonallergic anaphylaxis, angioedema. It can also be applied in cases of food allergy in Canada, Europe, and Mexico. The ketotifen recommended dose for adults and older children with allergic diseases or asthma is 1 mg twice daily. Ketotifen can be purchased online from trusted websites. With all that being said, it should also be mentioned that these days Ketotifen has become quite popular by its ability to inhibit the down regulation of beta receptors which are caused by drugs such as Clenbuterol. Ephedrine, Clenbuterol and albuterol are nowadays being used to be cycled on and off since they have the power to desensitize the various receptors they act on and thus to produce lipolytic effect. In other words, Ketotifen would allow the usage of the above mentioned fat burning drugs for much longer periods. Many medical experts state that Ketotifen is known for its ability to lower levels of the TNF-alpha or the cytokine Tumor Necrosis Factor-alpha. That is a catabolic hormone which lowers both the levels of the IGF-1 and the testosterone, and the strenuous exercise elevates the TNF-alpha levels. Further, the results show that TNF-alpha can increase the insulin resistance, which is not what we want.
How to use it for bodybuilding?
The regulation that Ketotifen can have on the beta-2 receptors make this drug interesting for the athletes and the bodybuilders. That is so, as the beta-2 receptors are supporting fat loss. Ketotifen is not in the role of a strong fat loss compound, however when being taken with a beta-2 agonist thermogenic drugs such as Clenbuterol, it can extend the active lipolysis and can increase the thermogenic potency. As a rule, Clenbuterol and the other beta-2 agonists usually have a limited duration of usefulness since the beta-2-adrenergic receptors decrease in number when there is a regular stimulation. That means that after several weeks of initiating therapy with such a drug, it usually begins to diminish in effectiveness. Here comes the role of the Ketotifen, which can considerably extend this time period. According to several studies that have been published, when Clenbuterol is taken along with Ketotifen, this results in a serious in the density of the beta-adrenergic receptor. Other studies of cases when Ketotifen was taken together with Albuterol showed that the beta adrenoceptor downregulation which has been caused by prolonged usage of the beta-adrenergic agent can be reversed with a daily dosage of just 2mg. The anti-histamine Ketotifen has been shown to stop the down-regulation of the beta receptors. For this reason, it is of great interest to bodybuilders and athletes. The daily dosage of 3mg of Ketotifen can clean the receptors and discard the need for short Clenbuterol cycles. In addition, it can heighten the effect of the drug in the body. To sum things up, when taking Ketotifen, one can limit the maximum daily dosage of Clenbuterol to 80-100mcg. Buy Ketotifen online only from trusted websites.
Ketotifen and Weight Loss
Ketotifen is usually taken by people suffering from wasting diseases, which are partially caused by the TNF-alpha. The ability of the drug to lower TNF-alpha is already overshadowed by the anabolic effects produced by the anabolic steroids. Ketotifen is usually used as part of the fat burning cycle including usage of Clenbuterol. Ketotifen is very valuable during the Post-Cycle-Therapy, thanks to its ability to lower TNF-alpha. By taking Ketotifen with the post-cycle therapy is a wonderful idea. The recommended dosage is 1-3 mgs/day before bed since that pill will make you pretty drowsy.
Ketotifen side effects
The side effects of Ketotifen include drowsiness and dry mouth, irritability and weight gain, and sometimes increased nosebleeds. Other side effects that can occur include headaches, increased sensitivity to light or runny/stuffy nose, as well as blurred vision. Ketotifen can also contact inactive ingredients, which can result in allergic reactions. However, many people who use Ketotifen do not complain from any serious side effects.
Being a selective antihistamine, Ketotifen is a mast cell stabilizer and an inverse agonist. It has also antiserotonergic and anticholinergic activity. When used with the right dosage, these anticholinergic and antiserotonergic activities of ketotifen are said not to be appreciable.
Where to buy ketotifen online?
There are trustworthy websites wherefrom one could buy Ketotifen online. With the proper dosage the Ketotifen drug taken along with Clenbuterol can give excellent results to all athletes and bodybuilders.